MDMA is a synthetic psychedelic, first developed by the pharmaceutical company Merck in 1912. It has been widely studied since then, particularly for psychotherapeutic uses. With the rate of academic research growing rapidly, it is likely that MDMA will become FDA approved for therapeutic use within the next few years, and MAPS.org is focused on moving it through the approval process. MDMA is being widely tested for post-traumatic stress, with results that surpass any other existing treatment method.
MDMA is a particularly appealing psychedelic for therapists and researchers because the subjective mental experience feels fairly stable, while creating a dramatic increase in emotional openness and a reduction in fear and anxiety.
Before you begin, be sure to read our safety section and see the special safety considerations for MDMA at the bottom of this page.
Because MDMA has anti-anxiety and anti-fear effects, it is generally considered safe to use a full dose your first time and each time you use MDMA (generally 75mg – 125mg depending on the individual). It is important to measure the dose carefully. Milligram-precision scales cost about 20 dollars (here’s an Amazon search for ‘milligram scale’).
Some therapy protocols add a ‘booster dose’ of about 60mg of MDMA 2-3 hours after the first dose to extend the period of therapeutic effects and provide more time for deep exploration.